Treatment of deep caries lesions in adults: randomized clinical trials comparing stepwise vs. direct complete excavation, and direct pulp capping vs. partial pulpotomy
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Treatment of deep caries lesions in adults: randomized clinical trials comparing stepwise vs. direct complete excavation, and direct pulp capping vs. partial pulpotomy. / Bjørndal, Lars; Reit, Claes; Bruun, Gitte Hoffmann; Markvart, Merete; Kjaeldgaard, Marianne; Näsman, Peggy; Thordrup, Marianne; Dige, Irene; Nyvad, Bente; Fransson, Helena; Lager, Anders; Ericson, Dan; Petersson, Kerstin; Olsson, Jadranka; Santimano, Eva M; Wennström, Anette; Winkel, Per; Gluud, Christian.
I: European Journal of Oral Sciences Online, Bind 118, Nr. 3, 01.06.2010, s. 290-7.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Treatment of deep caries lesions in adults: randomized clinical trials comparing stepwise vs. direct complete excavation, and direct pulp capping vs. partial pulpotomy
AU - Bjørndal, Lars
AU - Reit, Claes
AU - Bruun, Gitte Hoffmann
AU - Markvart, Merete
AU - Kjaeldgaard, Marianne
AU - Näsman, Peggy
AU - Thordrup, Marianne
AU - Dige, Irene
AU - Nyvad, Bente
AU - Fransson, Helena
AU - Lager, Anders
AU - Ericson, Dan
AU - Petersson, Kerstin
AU - Olsson, Jadranka
AU - Santimano, Eva M
AU - Wennström, Anette
AU - Winkel, Per
AU - Gluud, Christian
PY - 2010/6/1
Y1 - 2010/6/1
N2 - Less invasive excavation methods have been suggested for deep caries lesions. We tested the effects of stepwise vs. direct complete excavation, 1 yr after the procedure had been carried out, in 314 adults (from six centres) who had received treatment of a tooth with deep caries. The teeth had caries lesions involving 75% or more of the dentin and were centrally randomized to stepwise or direct complete excavation. Stepwise excavation resulted in fewer pulp exposures compared with direct complete excavation [difference: 11.4%, 95% confidence interval (CI) (1.2; 21.3)]. At 1 yr of follow-up, there was a statistically significantly higher success rate with stepwise excavation, with success being defined as an unexposed pulp with sustained pulp vitality without apical radiolucency [difference: 11.7%, 95% CI (0.5; 22.5)]. In a subsequent nested trial, 58 patients with exposed pulps were randomized to direct capping or partial pulpotomy. We found no significant difference in pulp vitality without apical radiolucency between the two capping procedures after more than 1 yr [31.8% and 34.5%; difference: 2.7%, 95% CI (-22.7; 26.6)]. In conclusion, stepwise excavation decreases the risk of pulp exposure compared with direct complete excavation. In view of the poor prognosis of vital pulp treatment, a stepwise excavation approach for managing deep caries lesions is recommended.
AB - Less invasive excavation methods have been suggested for deep caries lesions. We tested the effects of stepwise vs. direct complete excavation, 1 yr after the procedure had been carried out, in 314 adults (from six centres) who had received treatment of a tooth with deep caries. The teeth had caries lesions involving 75% or more of the dentin and were centrally randomized to stepwise or direct complete excavation. Stepwise excavation resulted in fewer pulp exposures compared with direct complete excavation [difference: 11.4%, 95% confidence interval (CI) (1.2; 21.3)]. At 1 yr of follow-up, there was a statistically significantly higher success rate with stepwise excavation, with success being defined as an unexposed pulp with sustained pulp vitality without apical radiolucency [difference: 11.7%, 95% CI (0.5; 22.5)]. In a subsequent nested trial, 58 patients with exposed pulps were randomized to direct capping or partial pulpotomy. We found no significant difference in pulp vitality without apical radiolucency between the two capping procedures after more than 1 yr [31.8% and 34.5%; difference: 2.7%, 95% CI (-22.7; 26.6)]. In conclusion, stepwise excavation decreases the risk of pulp exposure compared with direct complete excavation. In view of the poor prognosis of vital pulp treatment, a stepwise excavation approach for managing deep caries lesions is recommended.
KW - Adult
KW - Calcium Hydroxide
KW - Dental Caries
KW - Dental Cavity Lining
KW - Dental Cavity Preparation
KW - Dental Pulp
KW - Dental Pulp Capping
KW - Dental Pulp Exposure
KW - Dental Pulp Test
KW - Dental Restoration, Permanent
KW - Dental Restoration, Temporary
KW - Dentin
KW - Female
KW - Follow-Up Studies
KW - Glass Ionomer Cements
KW - Humans
KW - Male
KW - Middle Aged
KW - Minerals
KW - Periapical Tissue
KW - Pulpotomy
KW - Radiography, Bitewing
KW - Resin Cements
KW - Treatment Outcome
U2 - 10.1111/j.1600-0722.2010.00731.x
DO - 10.1111/j.1600-0722.2010.00731.x
M3 - Journal article
C2 - 20572864
VL - 118
SP - 290
EP - 297
JO - European Journal of Oral Sciences Online
JF - European Journal of Oral Sciences Online
SN - 1600-0722
IS - 3
ER -
ID: 33290833