Can the genotype or phenotype of two polymorphic drug metabolising cytochrome P450-enzymes identify oral lichenoid drug eruptions?
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Lichenoid drug eruptions (LDE) in the oral cavity are adverse drug reactions (ADR) that are impossible to differentiate from oral lichen planus (OLP) as no phenotypic criteria exist. Impaired function of polymorphic cytochrome 450-enzymes (CYPs) may cause increased plasma concentration of some drugs resulting in ADR/LDE. In an earlier study we did not find more patients with OLP (OLPs) with impaired CYP-genotype.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Journal of Oral Pathology & Medicine |
Vol/bind | 39 |
Udgave nummer | 6 |
Sider (fra-til) | 497-505 |
Antal sider | 9 |
ISSN | 0904-2512 |
DOI | |
Status | Udgivet - jul. 2010 |
Bibliografisk note
Paper id:: 20492431
ID: 21454348