Presence and consequence of tooth periapical radiolucency in patients with cirrhosis

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Standard

Presence and consequence of tooth periapical radiolucency in patients with cirrhosis. / Grønkjær, Lea Ladegaard; Holmstrup, Palle; Schou, Søren; Schwartz, Kristoffer; Kongstad, Johanne; Jepsen, Peter; Vilstrup, Hendrik.

I: Hepatic Medicine: Evidence and Research, Bind 8, 2016, s. 97-103.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Grønkjær, LL, Holmstrup, P, Schou, S, Schwartz, K, Kongstad, J, Jepsen, P & Vilstrup, H 2016, 'Presence and consequence of tooth periapical radiolucency in patients with cirrhosis', Hepatic Medicine: Evidence and Research, bind 8, s. 97-103. https://doi.org/10.2147/HMER.S113485

APA

Grønkjær, L. L., Holmstrup, P., Schou, S., Schwartz, K., Kongstad, J., Jepsen, P., & Vilstrup, H. (2016). Presence and consequence of tooth periapical radiolucency in patients with cirrhosis. Hepatic Medicine: Evidence and Research, 8, 97-103. https://doi.org/10.2147/HMER.S113485

Vancouver

Grønkjær LL, Holmstrup P, Schou S, Schwartz K, Kongstad J, Jepsen P o.a. Presence and consequence of tooth periapical radiolucency in patients with cirrhosis. Hepatic Medicine: Evidence and Research. 2016;8:97-103. https://doi.org/10.2147/HMER.S113485

Author

Grønkjær, Lea Ladegaard ; Holmstrup, Palle ; Schou, Søren ; Schwartz, Kristoffer ; Kongstad, Johanne ; Jepsen, Peter ; Vilstrup, Hendrik. / Presence and consequence of tooth periapical radiolucency in patients with cirrhosis. I: Hepatic Medicine: Evidence and Research. 2016 ; Bind 8. s. 97-103.

Bibtex

@article{ff205692cf684792a284e59ae069eeee,
title = "Presence and consequence of tooth periapical radiolucency in patients with cirrhosis",
abstract = "BACKGROUND: Periapical radiolucency is the radiographic sign of inflammatory bone lesions around the apex of the tooth. We determined the prevalence and predictors of periapical radiolucency in patients with cirrhosis and the association with systemic inflammation status and cirrhosis-related complications.METHODS: A total of 110 cirrhosis patients were consecutively enrolled. Periapical radiolucency was defined as the presence of radiolucency or widening of the periapical periodontal ligament space to more than twice the normal width. Predictors of periapical radiolucency and the association with systemic inflammation markers and cirrhosis-related complications were explored by univariable and multivariable logistic regression analyses.RESULTS: Periapical radiolucency was present in one or more teeth in 46% of the patients. Strong predictors were gross caries (odds ratio [OR] 3.12, 95% confidence interval [CI] 1.43-6.79) and severe periodontitis (OR 3.98, 95% CI 1.04-15.20). Also old age (OR 1.10, 95% CI 1.01-1.19) and smoking (OR 3.24, 95% CI 1.02-17.62) were predictors. However, cirrhosis etiology (alcoholic vs nonalcoholic) or severity (Model of End-Stage Liver Disease score) were not predictors. The patients with periapical radiolucency had higher C-reactive protein (15.8 mg/L vs 8.1 mg/L, P=0.02) and lower albumin contents (25 g/L vs 28 g/L, P=0.04) than those without. Furthermore, the patients with periapical radiolucency had a higher prevalence of cirrhosis-related complications such as ascites, hepatic encephalopathy, and/or variceal bleeding (46% vs 27%, P=0.05).CONCLUSION: Periapical radiolucency is often present as an element of poor oral health status and likely has an adverse clinical significance, which should motivate diagnostic and clinical attention to the findings.",
author = "Gr{\o}nkj{\ae}r, {Lea Ladegaard} and Palle Holmstrup and S{\o}ren Schou and Kristoffer Schwartz and Johanne Kongstad and Peter Jepsen and Hendrik Vilstrup",
year = "2016",
doi = "10.2147/HMER.S113485",
language = "English",
volume = "8",
pages = "97--103",
journal = "Hepatic Medicine: Evidence and Research",
issn = "1179-1535",
publisher = "Dove Medical Press Ltd",

}

RIS

TY - JOUR

T1 - Presence and consequence of tooth periapical radiolucency in patients with cirrhosis

AU - Grønkjær, Lea Ladegaard

AU - Holmstrup, Palle

AU - Schou, Søren

AU - Schwartz, Kristoffer

AU - Kongstad, Johanne

AU - Jepsen, Peter

AU - Vilstrup, Hendrik

PY - 2016

Y1 - 2016

N2 - BACKGROUND: Periapical radiolucency is the radiographic sign of inflammatory bone lesions around the apex of the tooth. We determined the prevalence and predictors of periapical radiolucency in patients with cirrhosis and the association with systemic inflammation status and cirrhosis-related complications.METHODS: A total of 110 cirrhosis patients were consecutively enrolled. Periapical radiolucency was defined as the presence of radiolucency or widening of the periapical periodontal ligament space to more than twice the normal width. Predictors of periapical radiolucency and the association with systemic inflammation markers and cirrhosis-related complications were explored by univariable and multivariable logistic regression analyses.RESULTS: Periapical radiolucency was present in one or more teeth in 46% of the patients. Strong predictors were gross caries (odds ratio [OR] 3.12, 95% confidence interval [CI] 1.43-6.79) and severe periodontitis (OR 3.98, 95% CI 1.04-15.20). Also old age (OR 1.10, 95% CI 1.01-1.19) and smoking (OR 3.24, 95% CI 1.02-17.62) were predictors. However, cirrhosis etiology (alcoholic vs nonalcoholic) or severity (Model of End-Stage Liver Disease score) were not predictors. The patients with periapical radiolucency had higher C-reactive protein (15.8 mg/L vs 8.1 mg/L, P=0.02) and lower albumin contents (25 g/L vs 28 g/L, P=0.04) than those without. Furthermore, the patients with periapical radiolucency had a higher prevalence of cirrhosis-related complications such as ascites, hepatic encephalopathy, and/or variceal bleeding (46% vs 27%, P=0.05).CONCLUSION: Periapical radiolucency is often present as an element of poor oral health status and likely has an adverse clinical significance, which should motivate diagnostic and clinical attention to the findings.

AB - BACKGROUND: Periapical radiolucency is the radiographic sign of inflammatory bone lesions around the apex of the tooth. We determined the prevalence and predictors of periapical radiolucency in patients with cirrhosis and the association with systemic inflammation status and cirrhosis-related complications.METHODS: A total of 110 cirrhosis patients were consecutively enrolled. Periapical radiolucency was defined as the presence of radiolucency or widening of the periapical periodontal ligament space to more than twice the normal width. Predictors of periapical radiolucency and the association with systemic inflammation markers and cirrhosis-related complications were explored by univariable and multivariable logistic regression analyses.RESULTS: Periapical radiolucency was present in one or more teeth in 46% of the patients. Strong predictors were gross caries (odds ratio [OR] 3.12, 95% confidence interval [CI] 1.43-6.79) and severe periodontitis (OR 3.98, 95% CI 1.04-15.20). Also old age (OR 1.10, 95% CI 1.01-1.19) and smoking (OR 3.24, 95% CI 1.02-17.62) were predictors. However, cirrhosis etiology (alcoholic vs nonalcoholic) or severity (Model of End-Stage Liver Disease score) were not predictors. The patients with periapical radiolucency had higher C-reactive protein (15.8 mg/L vs 8.1 mg/L, P=0.02) and lower albumin contents (25 g/L vs 28 g/L, P=0.04) than those without. Furthermore, the patients with periapical radiolucency had a higher prevalence of cirrhosis-related complications such as ascites, hepatic encephalopathy, and/or variceal bleeding (46% vs 27%, P=0.05).CONCLUSION: Periapical radiolucency is often present as an element of poor oral health status and likely has an adverse clinical significance, which should motivate diagnostic and clinical attention to the findings.

U2 - 10.2147/HMER.S113485

DO - 10.2147/HMER.S113485

M3 - Journal article

C2 - 27695370

VL - 8

SP - 97

EP - 103

JO - Hepatic Medicine: Evidence and Research

JF - Hepatic Medicine: Evidence and Research

SN - 1179-1535

ER -

ID: 167091961